Uic2 antibody

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August undefined, 2024

WebWithin the immune system, this molecule can be found on normal T, B, and natural killer cells, but not on monocytes. This antibody has been reported to inhibit MDR1-mediated efflux. Applications Reported: This UIC2 antibody has been reported for use in flow cytometric analysis. WebProduct Specific Information. This antibody does not react with mouse or rat. Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of …

P-Glycoprotein Monoclonal Antibody (UIC2) - Thermo …

Web5 Oct 2024 · Human-specific MRK16 antibodies were expressed from hybridoma cells, cultured in Wheaton CeLLine Bioreactors following the producer’s recommendation, similar to the previously published UIC2 antibody method , followed by Protein G (GenScript) affinity purification and fragmentation using Fab Preparation Kit protocol (Thermo Fisher). The … Web24 Aug 2024 · Despite the potential clinical application of this finding, the epitopes of the three human P-gp-specific monoclonal antibodies MRK-16, UIC2 and 4E3, which bind to … strong adjectives exercises pdf

Alexa Fluor® 647 anti-human CD243 (MDR-1) Antibody - BioLegend

Web19 Sep 2014 · The UIC2 monoclonal antibody recognizes human Pgp and inhibits its drug transport activity. However, this inhibition is partial, since UIC2 binds only to 10–40% of … Web13 Feb 2024 · Datasheets. MDR1/ABCB1 Antibody (UIC2) is a mouse monoclonal IgG 2a κ, cited in 31 publications, provided at 200 µg/ml. raised against MDR1 of human origin. … WebInvitrogen Anti-P-Glycoprotein Monoclonal (UIC2), Catalog # MA5-44031. Tested in Immunohistochemistry (Frozen) (IHC (F)), Immunohistochemistry (Paraffin) (IHC (P)), … strong adjectives english

CD243 (ABCB1) Monoclonal Antibody (UIC2), PE (12-2439-42)

R718 Mouse Anti-Human CD243

WebFlow Cytometry - APC Anti-P Glycoprotein antibody [UIC2] (ab272340) Separation of HepG2 (Human liver hepatocellular carcinoma cell line) cells (red-filled) from human peripheral whole blood cells (black-dashed) in … WebThe UIC2 monoclonal antibody specifically binds to an extracellular epitope of CD243, which is also known as ATP-binding cassette subfamily B member 1 (ABCB1), Multidrug resistance protein 1 (MDR1), or P-glycoprotein 1. CD243 is a transmembrane glycoprotein that spans the membrane 12 times. strong adjectives difficultWeb22 Jan 2013 · Product name PE Anti-P Glycoprotein antibody [UIC2] See all P Glycoprotein primary antibodies Description PE Mouse monoclonal [UIC2] to P Glycoprotein Host … strong adjectives for tired

"WebUIC2 is a monoclonal antibody that binds to the extracellular region of ABCB1, particularly extracellular loops 1, 3 and 4 [ 29 ]. Thus, it allows for labeling of cell surface-expressed ABCB1 without disrupting the plasma membrane. " - Uic2 antibody

Uic2 antibody

Anti Human CD243 Antibody, clone UIC2 Bio-Rad

Web27 Mar 2014 · Miele authored the 1997 Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products. In 1994, he … WebEach lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - …

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WebEach lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application. Web13 Feb 2024 · The ABCB1-specific inhibitory antibody UIC2 was developed with the goal of increasing antitumor drug treatment efficacy (8, 9). UIC2 targets the extracellular moiety of human ABCB1 (ABCB1 H ) and has been successfully used to investigate the transport cycle of ABCB1 owing to its ability to bind the transporter during various states of the catalytic …

WebTranslations in context of "méthodes se rapportant à" in French-English from Reverso Context: compositions et méthodes se rapportant à stop -1 WebThe UIC2 monoclonal antibody specifically binds to an extracellular epitope of CD243, which is also known as ATP-binding cassette subfamily B member 1 (ABCB1), Multidrug resistance protein 1 (MDR1), or P-glycoprotein 1. CD243 is a transmembrane glycoprotein that spans the membrane 12 times.

WebApplications Tested: This UIC2 antibody has been pre-titrated and tested by flow cytometric analysis on multidrug resistant cell lines. This can be used at 5 µL (0.5 µg) per test. A test … Web24 Aug 2024 · UIC2 antibody was prepared from hybridoma cells as described in the text. FITC-labeled anti-mouse secondary antibody IgG2a was obtained from BD Biosciences …

WebBuy mouse monoclonal (UIC2) antibody to CD243 (A121698). Validated Applications: Flow Cytometry. Reactivity: Human. ️ Low Prices ️ 100% Guarantee

WebThe UIC2 antibody reacts with an external epitope of the human P-glycoprotein (P-gp). UIC2 antibody inhibits Pgp-mediated efflux and potentiates the cytotoxic action of P-gp transported drugs in MDR cells. Customers Also Viewed. Life Sciences Division Headquarters 5350 Lakeview Parkway S Drive strong adjectives persuasiveWeb27 Sep 2024 · UIC2 shift assay ( a) was used to evaluate the impact of verapamil, paclitaxel, and DAC-2Amide, -3Amide and -4Amide on P-gp conformation. Normalized median fluorescence intensity (MFI) upon... strong adjectives happyWeb1 Dec 1999 · Because UIC2 is the only anti-P-gp MAb thus far described that blocks the effect of the pump (4), we carried out cross-blocking experiments to determine whether HD37 and UIC2 recognized the same epitope. This was accomplished using a standard cross-blocking protocol described previously (10). strong adjectives list for writing