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Pubmed statins

WebAug 17, 2024 · Statins have been recommended by several guidelines as the primary prevention medication for cardiovascular diseases. However, the benefits of statin therapy for cerebral small vessel disease (CSVD), particularly in adults ≥75 years of age, have not been fully evaluated. We analyzed the data from a prospective population-based cohort … WebApr 13, 2013 · During 1.2 million person-years of follow-up, there were 13,455 cases of type 2 diabetes and 8,932 deaths. Statin initiation was associated with increased risk of type 2 diabetes. The hazard ratio (95% CI) of diabetes was 1.45 (1.39–1.50) before adjusting for potential confounders and 1.14 (1.10–1.19) after adjustment.

Universal screening for familial hypercholesterolaemia in newborns

WebApr 14, 2024 · Abstract. High-risk neuroblastoma exhibits transcriptional activation of the mevalonate pathway that produces cholesterol and non-sterol isoprenoids. A better understanding of how this metabolic reprogramming contributes to neuroblastoma development could help identify potential prevention and treatment strategies. Here, we … WebJun 7, 2024 · Compared with non-statin users, statin users are usually older and have more comorbidities, which both lead to an increased risk of COVID-19 mortality [11, 12]. Thus, when the meta-analysis pooled the adjusted and unadjusted results, the association between statin use and mortality might not be obvious because the protective effect of … e.republic innovation https://australiablastertactical.com

Statin Adverse Effects: A Review of the Literature and …

WebWe conclude that statins contribute to macrophage-bactericidal activity against Mycobacterium bovis, M. leprae, and M. tuberculosis. It is likely that the association of … WebFeb 4, 2024 · Statins are important drugs that reduce cardiovascular risk factors and should be prescribed to appropriate patients with these risk factors but some of this population … WebLowering LDL cholesterol with statin therapy in people considered at low risk of atherosclerotic cardiovascular disease also lowers the risk of major vascular events, and … erepublic government technology

The effect of statins on average survival in randomised trials, an ...

Category:Advancing the CV Care of the Oncology Patient: Black Patients …

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Pubmed statins

Full article: Statins and muscle pain - Taylor & Francis

WebRhabdomyolysis is among the best-recognized and most feared complications of statins; it occurs when muscle damage is severe, leading to a marked elevation of CK (e.g. in … WebFeb 28, 2013 · Statins are extensively used for cardiovascular disease prevention. Statins reduce mortality rates more than other lipid-modulating drugs, although evidence from randomized controlled trials also suggests that statins unexpectedly increase the risk of diabetes and improve immune function. Physiologically, statins would be expected to …

Pubmed statins

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WebNov 10, 2024 · Statin therapy was associated with lower low-density cholesterol levels in patients treated with statins at follow-up (88 vs. 110 mg/dL, p < 0.001). In patients not on a statin, low-attenuation and fibro-fatty plaque volumes increased over time. In patients on a statin, coronary lesions had a lower volume of low-attenuation plaques and a higher ... WebIn contrast to the current belief that cholesterol reduction with statins decreases atherosclerosis, we present a perspective that statins may be causative in coronary artery …

WebObjective To estimate the average postponement of death in statin trials. Setting A systematic literature review of all statin trials that presented all-cause survival curves for … WebApr 14, 2024 · A. A. Black patients have 71% greater odds of cardiotoxicity following cancer treatment compared with White patients, according to a new meta-analysis presented at ACC's Advancing the Cardiovascular Care of the Oncology Patient 2024 conference taking place April 14-16 in Washington, DC, and virtually. Wondewossen Gebeyehu, BSc, et al., …

WebObjective Statins are commonly prescribed cholesterol-lowering drugs. Preclinical studies suggest that statins may possess cancer preventive properties. The primary objective of this meta-analysis was to determine the association between statin use and risk of liver cancer. Design Meta-analysis. Setting International. Participants A comprehensive literature … WebJul 16, 2016 · With so many people eligible for treatment, even rare adverse effects become important. In 2012, the U.S. Food and Drug Administration (FDA) issued a statement regarding rare postmarketing reports of ill-defined cognitive impairment associated with statin use that was reversible upon statin discontinuation ().This has led many people, …

WebHowever, results of individual studies were inconsistent, with 1 large trial (JUPITER) showing increased diabetes risk. 27 This could be due to JUPITER being the only trial to use high-potency statin therapy; other analyses that included trials of statins for secondary prevention suggest an association between intensity of statin dose and risk of incident …

WebMar 6, 2024 · Among patients receiving contemporary statins, inflammation assessed by high-sensitivity CRP was a stronger predictor for risk of future cardiovascular events and death than cholesterol assessed by LDLC. These data have implications for the selection of adjunctive treatments beyond statin therapy and suggest that combined use of … e reputation leroy merlinWebFeb 5, 2024 · Statin medications are used in the management and treatment of hypercholesteremia. ... 2024 Nov 17 [PubMed PMID: 32956597] Strilchuk L,Tocci G,Fogacci F,Cicero AFG, An overview of rosuvastatin/ezetimibe association for the treatment of hypercholesterolemia and mixed dyslipidemia. find middle school yearbooksWebJul 27, 2024 · To reflect changes in the use of statin over time (e.g., new initiation or discontinuation, change to other statins), statin use was defined as a time-varying … find middle school yearbooks online free