WebDec 6, 2024 · National Center for Biotechnology Information WebNov 26, 2012 · In the salvaged eyes, MK resolved in 9 eyes (90%) on medical treatment at a mean duration of 30 days and keratoplasty was performed in 1 eye. OSSN treatment included wide excisional biopsy (n = 9/18; 50%), extended enucleation (n = 7/18; 39%), and orbital exenteration in 1.
National Center for Biotechnology Information
WebJan 9, 2024 · Most patients with ocular surface squamous neoplasia (OSSN) respond to treatment with topical 5-fluorouracil (5FU) eye drops, with complete resolution achieved in 87% of eyes treated, according to results of a study published in The Ocular Surface.The study shows efficacy in 2 years worth of follow up with minimal side effects. WebThe median time to OSSN resolution was 2.8 months in the 1 million IU/ml group and 1.9 months in the 3 million IU/ml group, p=0.55. Neither eye with SCC responded to interferon therapy. Topical therapy was well tolerated. … edmtooling.com
Optometric Clinical Practice
WebJan 1, 2024 · To our knowledge, this is the largest long-term retrospective study of OSSN patients who underwent primary treatment with topical 5FU 1% eye drops. Complete resolution of OSSN using topical 1% 5FU was achieved in 87% of treated eyes, with modest side effects. Resolution occurred in both small and large tumors. WebOcular surface squamous neoplasia (OSSN) is a common malignancy of the squamous epithelium of the conjunctiva and cornea that comprises of the wide spectrum of … WebJun 15, 2024 · Introduction This study evaluated the efficacy of combined interferon α-2b (IFNα2b) and 5-fluorouracil (5-FU) as primary treatment for ocular surface squamous neoplasia (OSSN). Methods In this retrospective study, 27 eyes with OSSN followed by topical application of combined IFNα2b and 5-FU were examined. Reported outcome … edm to halifax