WebDrug-induced liver injury (DILI) is considered gradually as a serious public health issue, and hepatotoxicity has been regarded as the main clinical problem caused by it. We suspected that both the intracellular viscosity and peroxynitrite (ONOO–) levels in drug-induced hepatotoxicity tissue are higher than those in a healthy liver. For this reason, we have …
Multifunctional Fluorescent Probe for Simultaneous Detection of ONOO …
WebWago Web16 de mai. de 2024 · Peroxynitrite (ONOO-), an important reactive oxygen species (ROS), may be generated in the mitochondria under various physiological and pathological … iowa high school football schedule 2021
Visualization of ONOO - and Viscosity in Drug-Induced ... - PubMed
Web20 de mar. de 2024 · The probe exhibited a remarkable turn-on response to ONOO – with the far-red emission of about 645 nm and was highly sensitive to viscosity/polarity in the NIR channel with λ em > 704 nm. Facilitated by MQA-P , for the first time, we revealed that erastin-induced ferroptosis was accompanied by a significant upregulation of ONOO – … WebDownload scientific diagram Peroxynitrite (ONOO ) causes greater force reduction in slow-twitch fibers. A and B: 2 force-pCa staircases elicited both before and after exposure to … Web1 de jul. de 2024 · The fluorescent probe, GXY-ADP-2, with xanthene structure as the fluorescent core was designed and prepared for the selective detection of peroxynitrite (ONOO-). ONOO- can be produced endogenously and exogenously and is a strong oxidant with a short half-life. Oxidative modific … openarcgisonlinesharedwebmap