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Nettet18. jan. 2008 · Using a yeast 2-hybrid screen of a peripheral lymphocyte cDNA library to identify cDNAs encoding proteins that interact with RAP74, followed by screening colon carcinoma and fetal brain cDNA libraries, Archambault et al. (1998) isolated cDNAs encoding CTDP1, which they called FCP1 (TFIIF-associating CTD phosphatase-1). … Nettet18. feb. 2003 · Although multiple kinases target the CTD of RNAPII, the only protein phosphatase known to dephosphorylate the CTD is FCP1. FCP1 was identified in both mammalian cells (13–15) and Saccharomyces cerevisiae (16, 17).Dephosphorylation of the CTD of the largest subunit of RNAPII by FCP1 can facilitate recycling of the … to lady\u0027s-thumb
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